

14 Throughout the day, the eye is exposed to environmental irritants-wind, dust, smoke, allergens-to which the ocular surface must respond, in order to maintain a homeostatic balance. 14 Contact lens wearers who experience dryness symptoms often report that they worsen toward the end of the day, and indeed, tear fi lm osmolarity has been shown to increase from the beginning to the end of the day in wearers of daily soft contact lenses. There may also be localized increases in osmolarity, for example, in areas overlying tear thinning/ breakup between blinks. This variable osmolarity across the ocular surface (increasing from the upper meniscus to the lower conjunctival sac) is infl uenced by tear secretion, drainage, and blink/spreading dynamics. It changes throughout the day and even differs depending on the “compartment” or portion of the ocular surface from which a sample is taken. 1 Just as the tear fi lm is dynamic, always changing, so osmolarity is not a fi xed, static measurement. These promising early data suggest that Bausch + Lomb INFUSE ™ contact lenses could become the SiHy daily disposable lens of choice for many of our patients. Patients with a history of contact lens dryness had an exceptionally positive wearing experience, rating lenses highly across comfort and vision parameters. The impact of this engineering is evident in the performance of Bausch + Lomb INFUSE ™ lenses. 11,35 Bausch + Lomb INFUSE ™ contact lenses combine a next-generation lens material with the innovation of ProBalance Technology ™, to help maintain ocular surface homeostasis in contact lens wearers and help reduce symptoms of contact lens dryness and discomfort.

In addition to the insertion of the lens itself, a number of patient-specifi c and/or environmental factors-tear quality, frequency and completeness of blinking, and/or environmental exposures-can change the balance on the ocular surface. 21,34 Nevertheless, contact lens wearers-even those in SiHy daily disposables-may experience discomfort or dryness symptoms that may be related to alterations in ocular surface homeostasis. Materials with higher moisture content, lower modulus, and excellent oxygen permeability have become available and been paired with the daily disposable modality, which helps to achieve the goal of helping to maintain ocular surface homeostasis. 15 TEAR FILM OSMOLARITY DYNAMICS ADVANCING INNOVATION IN PRACTICE The SiHy contact lens category has been evolving over the last 20 years, with the goal of minimizing the impact on the ocular environment. 15 Considering the visually demanding lifestyles of the patients in this study, it is remarkable that 90% agreed Bausch + Lomb INFUSE ™ lenses delivered comfortable vision throughout the day, and 87% noted that the lenses provided clear vision when working for long hours at a computer.

15 95% of patients had a positive overall impression of Bausch + Lomb INFUSE ™ lenses Wearers in this study (89%) also agreed that Bausch + Lomb INFUSE ™ lenses made their eyes feel comfortable and healthy, and 91% agreed that the lenses helped maintain healthy, white eyes. This contrasts starkly with the survey data noted above, in which nearly 70% of SiHy daily disposable wearers said they had to settle for less comfort in order to keep wearing lenses throughout the day.
